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Tirzepatide activates two: GLP-1 and GIP (glucose-dependent insulinotropic polypeptide)

The critical requirement is a minimum of 48 hours between injections to avoid creating amplified drug peaks

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What About Drug Interactions

Dose reduction and stabilization For users who have reached the full 2.4mg dose and find bloating intolerable despite dietary modifications and OTC remedies, dropping back to 1.7mg or even 1.0mg may be appropriate