Anaphylactic reactions to thiamine are exceedingly uncommon (estimated incidence well below 1 %), but they have been documented
The manufacturing process for vitamin b1, b6, and b12 involves series of steps including drug development, synthesis, formulation, and filtration etc
When your body does absorb B12, it takes time for the vitamin to be distributed throughout the body and more time for the body to use it in a way that is noticeable
High-dose biotin, also known as vitamin B7, can affect assays that use a biotin and streptavidin binding step, and the direction of the error depends on the assay format, with competitive designs prone to falsely high results and sandwich designs to falsely low ones
Taking B12 with food, switching to a different formulation, or trying a liquid preparation may reduce nausea