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One prime example is the discovery of the nutrient sensing mechanism for cholesterol, which led to the development of life-saving statin drugs (and the Nobel Prize)

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The pathophysiological processes in PD, including oxidative stress, protein misfolding, mitochondrial dysfunction and neuroinflammation, overlap with those observed in type 2 diabetes (T2D) [2,3,4,5]

This is why they are effective in improving blood sugar control for those with type 2 diabetes and promoting weight loss via decreased appetite and energy intake

The attachment of octanoic acid to Ser3 of ghrelin is accomplished by the acyltransferase originally identified as ghrelin O -acyltransferase, GOAT