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Because it stimulates the central nervous system, bupropion may cause anxiety or restlessness in sensitive individuals

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Transcriptomic analysis revealed significant differences in small intestinal GLP-1-secreting L-cells from GF versus conventional mice, including increased GLP-1 content in GF mice, which was rapidly altered following conventionalization, implicating a strong role of the gut microbiota in regulating EEC physiology 243

& Franchini, S