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The compound is not listed as a scheduled controlled substance under the international drug-control conventions or under the major national scheduling systems

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The hydrogenases and, by necessity, enzymes associated with cobalt utilization, involve metal-carbon bonds

Overdose of B12 can cause anxiety, acne, skin redness, headache, nausea, vomiting, heart stroke, face paralysis, palpitations, facial ruddiness, and insomnia