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Safe Compounding vs High-Risk GLP-1 Sources Legitimate compounded GLP-1 medications : Use pharmaceutical-grade active pharmaceutical ingredients (APIs) Are sterile, potency-tested, and traceable Require a prescription and clinician oversight High-risk red flags include : Prices far below typical market cost No physical address or phone number Research chemical or not for human use labeling Semaglutide or tirzepatide promoted as salts DIY powder-and-diluent kits No Certificate of Analysis (COA) Missing lot number or Beyond-Use Date (BUD) No prescription requirement How to Safely Choose Compounded Semaglutide or Tirzepatide (When Medically Necessary) When compounding is appropriate, patients should verify,: U.S.-licensed pharmacy or FDA-registered outsourcing facility API sourcing compliant with Import Alert 66-80 (Green List) Certificate of Analysis (COA) verifying identity and purity Sterile, ready-to-inject medication Lot number and Beyond-Use Date (BUD) Transparent pricing consistent with pharmaceutical-grade sourcing Physician oversight and follow-up care Frequently Asked Questions Is compounded semaglutide legal in 2026