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Patients should also contact their provider before starting semaglutide if they have a history of pancreatitis, severe gastrointestinal disease, diabetic retinopathy, medullary thyroid carcinoma, or MEN2

One major difference between the two types of GLP-1s is dosage

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The demographic most commonly prescribed semaglutidemiddle-aged and older adults with obesity and metabolic conditionshas a high baseline prevalence of osteoarthritis, inflammatory arthritis, and other musculoskeletal disorders

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