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Platelets contain alpha granules packed with growth factors: platelet-derived growth factor (PDGF), transforming growth factor beta (TGF-B), insulin-like growth factor (IGF-1), and others

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Human Studies Human data remain limited, and most studies are small, single-center, or use copper peptide formulations combined with other ingredients (which makes it hard to isolate GHK-Cu's specific contribution): A 2016 Lee et al

Such gout tophus draining presents a risk of infection, since bacteria can track back through the skin and form a deep infection