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The exploited pancreatic pre-neoplastic lesion organoid transplantion in syngeneic mouse model resulted a good approximation of human PDAC pathology, which develops slowly together with desmoplasia establishment [46, 56, 57]

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One reason is that by reducing appetite, these drugs may help individuals develop healthier eating habits, such as reduced portion sizes or more nutritionally-balanced meals, and these habits may persist even after treatment is discontinued