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The study utilized white non-thoroughbred male rats weighing 180-200g

Peeters, S

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These peptides, which include glucose-dependent insulinotropic peptide (GIP) and GLP1, are responsible for the incretin effect, which explains why the stimulus for insulin release is stronger upon receiving an oral glucose load, rather than an intravenous one.40,41 Dipeptidyl peptidase 4 (DPP-4) is the protein that cleaves and inactivates GLP-1 and GIP in a few minutes,40 thus the medications that inhibit said aminopeptidase increase the circulating levels of the incretins, enabling the stimulation of glucose-dependent insulin secretion in the pancreatic islets, through membrane receptors in the cells, to persist.41 Sitagliptin, linagliptin, saxagliptin, vildagliptin, and alogliptin, among others, belong to the group of DPP-4 inhibitors (iDDP-4)

Remission of prurigo pigmentosa after breaking ketogenic diet and resuming regular diet