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Byrne said GLP-1 patients often walk into his office claiming they look hollowed out. Think sunken cheeks, gaunt eyes, sagging neck skin, surprise jowls and temples that seem to have caved in overnight

Abdominal massage

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Thus, in perfect agreement with the recent ADA-EASD consensus report [6], we also encourage the adoption of GLP-1RA plus SGLT2i combination therapy in T2DM patients with established ASCVD (coronary artery disease, cerebrovascular disease, or peripheral arterial disease) or multiple risk factors for ASCVD (i.e., age 55 years, obesity, dyslipidemia, hypertension, current tobacco use, left ventricular hypertrophy, and/or proteinuria) whose HbA1c remains suboptimal despite initial treatment with only one of these agents

Tirzepatide : Activates both GLP-1 and GIP receptors, which may provide additional metabolic support and appetite regulation