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These surgical techniques for direct stone removal are reserved for cases, usually with larger stones, when other methods are not appropriate (Antonelli 2015)

Buse JB, DeFronzo RA, Rosenstock J et al (2016) The primary glucose-lowering effect of metformin resides in the gut, not the circulation: results from short-term pharmacokinetic and 12-week dose-ranging studies

As the long-acting (more potent) GLP-1 RAs liraglutide, semaglutide and dulaglutide [1, 2] are becoming the standard in treatment, we focused on these agents

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