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As a relatively new compound, data on 5-Amino-1MQs side effects is still developing

However, the discovery of functional extrinsic death receptor-mediated eryptosis and necroptosis of erythrocytes associated with the necrosome formation opens new horizons for our understanding of the possible role of caspases in mature erythrocytes, since caspase-8 might be involved in coordinating the cell fate of mature erythrocytes

More recently, it is becoming well-recognized that a better understanding of cellular signaling pathways alternation under toxicological insult will benefit the risk assessment and early stage prediction of drug toxicity (Jennings et al., 2013)

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