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Jul 1 1997 De Flora et al., European Respiratory Journal, doi:10.1183/09031936.97.10071535 Attenuation of influenza-like symptomatology and improvement of cell-mediated immunity with long-term N-acetylcysteine treatment RCT 262 elderly and/or chronic disease patients in Italy showing significantly reduced frequency and severity of influenza-like episodes with 600mg N-acetylcysteine twice daily for 6 months

Common Side Effects Most side effects are temporary and mild

Cytokine production and response are important as they participate in immune and inflammatory responses

Pairing with calming HA definitely helps mitigate this