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Variants in the GLP1R gene (rs6923761) and MC4R gene (rs17782313) affect how well your body responds to GLP-1 receptor activation, meaning some patients achieve deep satiety from smaller oatmeal portions while others need slightly larger servings to feel the same effect

Studies suggest semaglutide might have a stronger impact on weight loss compared to other GLP-1 agonists like dulaglutide

Think of it as a warm-up, giving your body a chance to ease into the process

In PIONEER 3, mean weight loss was -1.3% with semaglutide 3 mg, -2.2% with semaglutide 7 mg, -3.2% with semaglutide 14 mg and -0.6% with sitagliptin from baseline to week 26

Inoltre, uno stato di euglicemia permette di ridurre i livelli sierici di prodotti avanzati della glicazione (AGEs) e di prodotti proteici avanzati dellossidazione (AOPPs) tipicamente associati alliperglicemia e determinanti danno renale