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Research since 2023 has shown improvements in ovulation and menstrual regularity for some patients using GLP-1s (Escobar-Morreale et al., 2024)

This calculation is straightforward, but patients consistently underestimate how quickly they will move through vials as doses escalate

Neither Mounjaro nor Semaglutide is suitable for people with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2

The candidates that exist in 2026 are: clinician judgment (the gold standard, but in short supply), expanded laboratory work (DEXA for body composition, CGM for glycemic patterns, metabolic panels of increasing sophistication), patient-reported priorities (the founder who tells you he cares about muscle is providing useful prior information), and, increasingly, genetics

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