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doi: 10.1007/s12282-017-0812-x 198 HouXZhaoMWangTZhangG

Weight loss typically accelerates as the dose is gradually increased over 16 weeks to the maintenance dose of 2.4 mg weekly for weight management

Moreover, this effect of L-carnitine on protein synthesis was consistent with that of protein expression, mitochondrial function, and cell survival (Figure 5), suggesting that these deleterious effects of lenvatinib were primarily caused by its inhibitory action on protein synthesis

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