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Hypothalamic dysfunction is a common finding in PWS and it has been implicated in several manifestations of this syndrome such as hyperphagia, temperature instability, high pain threshold, sleep disordered breathing, and multiple endocrine abnormalities
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Initially developed for glycemic control in diabetic patients, recent clinical findings have revealed their profound effects on weight loss, cardiovascular health, and metabolic regulation
A few declared that they will immediately stop compounding GLP-1s that are no longer in shortage, while others have vowed to tweak presentations or formulations to attempt to avail themselves of the significant difference exception under 503A or the clinical difference exception under 503B
doi: 10.1016/j.freeradbiomed.2016.08.026 62 TangK-TLinC-CLinS-CWangJ-HTsaiS-W
