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Today, medical guidelines remain cautious, but they now recognize that GLP-1s might help some people with type 1 diabetes, especially those with insulin resistance or excess weight

For the scenario of "Male erectile dysfunction unresponsive to PDE5 inhibitors," research data suggests Alprostadil may be more relevant

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Sodium is a primary driver of water retention

SRD5A1 is predominantly expressed in skin and annexes 23,25,26