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b , representative PSR stained liver sections, quantification is provided in Fig

In general, disordered domains are unsuitable targets for potent peptide binding because of the lack of well-defined binding surfaces, conformational flexibility, and associated entropic penalties 60,61

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Cell proliferation needs more oxygen and energy supply

In addition to viral replication, these proteins can trigger responses and induce cytotoxic and pro-inflammatory effects in neurons, dendritic cells (DCs), microglia, and macrophages, and astrocyte across the CNS, thereby contributing to the development of NeuroHIV [35,36,37]