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Second, similar to DC antigen presentation, B cells bind antigens via B cell receptors (BCRs), process them into short peptide fragments via endocytosis, and present them with MHC class II molecules to Th1 and Th17 cells to activate T cells (130)

The relative abundance of Bifidobacterium , Lactobacillus , Coprobacillus , Ruminococcus , Prevotella , and Blautia was significantly higher after supplementation, and the abundance of Shigella and Clostridium was significantly lower, meaning that probiotic supplementation regulated the intestinal flora [115]