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However, both compounds individually cause: Nausea (60-80% of users at higher doses) Vomiting (20-35%) Diarrhea (25-40%) Injection site reactions (15-25%) Potential pancreatitis (rare but serious) Combining these compounds could theoretically amplify these effects, though the actual incidence and severity remain unstudied

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Consequently, increased reactive oxygen species levels lead to decreased levels of reduced GSH and increased levels of TGF-, which has been demonstrated to inhibit the rate-limiting enzyme responsible for the de novo synthesis of GSH