what is the difference in tirzepatide and semaglutide vs vs Liraglutide Semaglutide vs. Tirzepatide - Global

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Early detection has allowed for cures exceeding 95%

Semaglutide (Ozempic/Wegovy) Timeline Phase 3 trials began: 2015 (SUSTAIN program for diabetes) FDA approval (Ozempic for diabetes): December 2017 Commercial availability: Early 2018 Wegovy (obesity indication) Phase 3: 2018-2020 (STEP program) Wegovy FDA approval: June 2021 Wegovy commercial launch: September 2021, immediately went into shortage due to overwhelming demand Stable widespread availability: Mid-2023 (after Novo Nordisk scaled up manufacturing) Total time from Phase 3 start to stable availability: About 8 years for diabetes indication, 5 years for obesity indication (but with significant supply constraints)

Systemic injection (into abdominal fat or another convenient site) allows the peptide to distribute throughout the body and migrate to damaged areas