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Epigallocatechin-3-gallate (EGCG) improves cognitive deficits aggravated by an obesogenic diet through modulation of unfolded protein response in APPswe/PS1dE9 mice

& Greenberg, J

This unique enzymatic mechanism directly couples sirtuin activity to cellular NAD+ availability, making these longevity proteins exquisitely sensitive to cellular energy status and NAD+ levels

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