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doi: 10.1021/bi00013a002 140 SagaramU

Several biological factors may influence the timing of appetite-related observations, including: GLP-1 receptor sensitivity Body composition Metabolic rate Hormonal environment Age Existing metabolic characteristics These differences explain why two otherwise similar research subjects can produce different timelines despite following identical protocols

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The dysregulation of the pituitary GH and hepatic insulin-like growth factors (IGFs) affects many cellular processes associated with growth promotion, including protein synthesis, cell proliferation and metabolism, leading to growth disorders