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GLP-1 medications tend to produce relatively rapid fat loss, which increases the likelihood of excess skin compared to gradual weight loss through diet and exercise alone

[364] [365] [366] Idiopathic intracranial hypertension (IIH) Obesity is a well-established risk factor in developed countries, and diets contributing to obesity may lead to nutritional deficiencies associated with the clinical symptoms of Idiopathic Intracranial Hypertension (IIH)

In addition, psychological testing and therapist evaluation both pointed to a positive change in ego functioning after DSIP , suggesting greater resilience to stress and a more positive outlook on life

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This is potentially important, as there is some evidence pointing to a role for mitochondrial abnormalities in bipolar disorder although this remains controversial