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Anguo Wu: Supervision, Conceptualization, Funding acquisition, Writing original draft, Writing review & editing

Agents such as liraglutide (3.0 mg daily) and once-weekly semaglutide have been approved for obesity treatment, achieving weight reductions of approximately 515% in many patients Highdose GLP-1RAs significantly reduce body weight by suppressing appetite and calorie intake [234]

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