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This dual agonist effect not only enhances insulin secretion in response to meals but also slows gastric emptying, which helps patients feel fuller for longer
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Inducers of CYP3A4 The concomitant use of Oxycodone and Acetaminophen Tablets and CYP3A4 inducers, such as rifampin, carbamazepine, and phenytoin, can decrease the plasma concentration of oxycodone [see CLINICAL PHARMACOLOGY], resulting in decreased efficacy or onset of a withdrawal syndrome in patients who have developed physical dependence to Oxycodone and Acetaminophen Tablets [see WARNINGS]
While the exact mechanism remains debated, clinical observations suggest that B12 supplementation reduces nausea severity in a subset of users