Alcohol use specifically can have changes in consumption affect healing after extractions and periodontal procedures, sedation response, and overall soft tissue health
While mice and rats do not vomit, GLP-1R agonism induces emesis in the musk shrew and is associated with an increase in cFOS staining in the AP, nucleus of the solitary tract (NTS), DMH, VMH, lateral hypothalamus (LH), and PVH that is blocked by GLP-1R antagonism (77)
In these cases, a combination of non-stimulant medications, therapy, and lifestyle changes can provide effective results without the risks
The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: Evidence from human genetic association studies and a mouse model of alcohol dependence
Lancet 2023;402:72030.ArticlePubMed 11