semaglutide approved by insurance said no. That doesn't mean you're out of options. Most plans don't cover for weight loss Is Semaglutide Covered by Insurance?

As access to compounded GLP-1 injections recently became increasingly restricted, many patients turned to the gray market an underground network where medications are sold outside regulated pharmacies

Beyond their established metabolic actions, GLP-1RAs exert pleiotropic effects relevant to neurodegeneration, including modulation of neuroinflammation, mitochondrial function, oxidative stress, excitotoxicity, and cell-survival signaling, with selected agents demonstrating central nervous system penetration

10.1016/j.regpep.2012.12.007 9 BecejacT.CesarecV.DrmicD.HirslD.MadzaracG.DjakovicZ.et al (2018)

The association for bipolar disorder was significant in Hou Ls study (OR = 0.90, 95% CI [0.88, 0.93]) but lacked statistical significance in Stahl Es analysis

Only one study hid the allocation method