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619 Eliapixant in patients with DNP did not translate to any relevant improvement in different pain intensity outcomes compared with placebo in phase 2a of the PUCCINI study

11 , e002203 (2024)

In vivo, intrastriatal 3-HK alone produces limited neuronal loss, but co-administration with QA results in synergistic excitotoxic and oxidative injury that is attenuated by NMDAR antagonists and free radical scavengers [156]