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doi: 10.4239/wjd.v7.i17.354 [DOI] [PMC free article] [PubMed] [Google Scholar] 72

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7,8 In patients with chronic heart failure, adding Ubiquinol to statin therapy can elevate reduced CoQ10 levels, which can support skeletal and cardiac muscle health 9 there is a strong case for considering co-administration of ubiquinol with statin therapy in patients with depressed or borderline myocardial function. we believe that the co-administration of 300 mg ubiquinol with the combination ezetimibe/statin should be the preferred initial therapeutic option for LDL-lowering in patients with heart failure and hypercholesterolaemia, especially in those with high oxidative stress and coronary artery disease. Kloer H-U, Belardinelli R, Ou R, Rosenfeldt F