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the numbers look larger but the design cannot support a head-to-head claim.9 In paediatric type 1 there are no Phase 3 trials at all, a gap ISPAD 2024 flags explicitly.6 Longer, larger AID-era trials with hard outcomes, paediatric data, and head-to-head tirzepatide RCTs would all strengthen it

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Deane, A.M., et al

Discussion and Future Perspectives A better understanding of the metastatic processes that govern migration of primary melanoma to distant metastatic niches such as lymph nodes, liver, lung, and brain can aid in the clinical development of novel anti-cancer treatments in the future