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The benefit of AOX supplementation on progressive sperm motility was also confirmed by the analysis performed after the exclusion of studies carried out in patients with varicocele or treated with varicocele repair and AOX or placebo/no treatment [28, 31, 32], including a total of 1,923 infertile men (weighted MD 7.78% [95% CI: 3.86, 11.70]

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Therefore, a phospholipid concentration of 7% was selected for subsequent studies, under which the liposomes exhibited optimal stability (Fig

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