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In the initial stages of the disease, patients can also be referred to an optometrist to perform a slit lamp examination to determine the presence of KF rings

Application of functional genomics to pathway optimization for increased isoprenoid production

Nevertheless, they represent a great advance in investigation technology and their attempt to biomimicking cell and tissue environment is a crucial advantage compared to 2D cultures and a promising complement to animal model studies with great potential for further investigation of ECD in the context of CVDs

Non- compartmental pharmacokinetic parameters were calculated from serum drug concentration- time profiles by use of WinNonlin software (Pharsight, Mountain View, CA, USA)

When introducing your chosen diluent, direct the needle against the inner glass wall of the vial