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Existing studies have often failed to adequately consider how biological and psychosocial factors may differ between men and women, leading to potential biases in understanding the impact of alcohol on mood disorders

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on the other hand, aberrant DNA methylation may lead to the silencing of pro-ferroptosis genes such as the GPX4 promoter region, thereby inducing ferroptosis (Zhang et al., 2022)

J Tripathi A, Debelius J, Brenner DA, Karin M, Loomba R, Schnabl B, Knight R (2018) The gut-liver axis and the intersection with the microbiome