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The homologous cytochrome CYP2A6 of humans in Cyp2a5 mice is expressed in several liver diseases by the induction of toxic chemicals [77], where the levels of mRNA and Cyp2a5, on comparison between knockout NRF-2/ and wild-type mice, proved the increase of NRF-2 and Cyp2a5 in wild-type mice, as well as their interaction by co-immunoprecipitation Cyp controlled by NRF-2 [77]

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It is not surprising that the T cell motility machinery is integrated with abnormal lipid metabolism, as the turnover of membrane structure in migrating T cells largely relies on lipid availability

The activity of dipeptidase can be assayed with a HPLC method using glycyl-D-phenylalanine as described by Littlewood et al