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B, mid small bowel segment

Phosphatidylcholine, a primary component of lecithin, is converted in the brain into the neurotransmitter acetylcholine.*

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We also assess the methodology and data used to develop the recommendations submitted to us by the RUC and other public commenters and the rationale for the recommendations

ALS-linked P56S-VAPB, an aggregated loss-of-function mutant of VAPB, predisposes motor neurons to ER stress-related death by inducing aggregation of co-expressed wild-type VAPB