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Additionally, the weight loss achieved with these medications often leads to improved self-esteem, body image, and physical functioning, all of which can positively influence mood

However, there are certain individuals and conditions who should avoid or use GLP-1s with caution

Secondly, it may activate short-chain fatty acid receptors (SCFA receptors) and inhibit histone deacetylase (HDAC) activity, thereby lifting transcriptional repression on key iron absorption genes (such as Dcytb and Ferroportin) and consequently upregulating intestinal iron uptake