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GLP-1
This dual action creates an environment where muscle tissue is actively protected while fat stores are preferentially mobilized for energy
Clinical trials of semaglutide showed an average weight loss of about 15% over 68 weeks
Increasing Insulin Secretion: By activating GLP-1 receptors on pancreatic beta cells, semaglutide enhances insulin secretion in response to elevated blood glucose levels
Studies indicate that adverse event discontinuation rates for dual therapy range from 2% to 5%, suggesting that most patients tolerate the combination well enough to benefit from longer-term treatment
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