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Long R3 IGF-1 is, despite occasional terminology confusion in the gray literature, the same compound as IGF-1 LR3

PlexusDx partners only with licensed 503A compounding pharmacies that follow strict quality standards to maximize stability within this 28-day window

Because appetite is so suppressed, hitting that target usually means choosing protein sources that pack more nutrition into a smaller volume of food, rather than relying on volume to get there

By: Cami Eastman, RDN, LD on 02/26/2026 As more people in midlife turn to GLP-1 medications for metabolic support, questions are emerging about how these drugs interact with hormone replacement therapy (HRT), what the long-term effects may be for postmenopausal bodies, and what nutritional strategies are most important to protect health

They can be combined: NAD+ helps fuel the machinery peptide signals rely on, so a physician designed, supervised plan may use both