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Abstract Background: Oxidative stress can result from redox reactions involving hemoglobin (Hb) and nitric oxide (NO), forming toxic peroxynitrite when NO reacts with superoxide during Hb autoxidation

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Figure 7 LA Supplementation Prevented FA-Induced xCT Reduction by Inhibiting p53 Activation P53 served as a major factor of cellular ferroptosis that respond to various injuries, and we further examined whether LA can protect from ferroptosis that was associated with p53 activation in tubular epithelial cells

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