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If you have a vitamin B12 deficiency, injections are the best option because they bypass the GI tract, where the body loses some of the vitamin from oral supplements

Tuttle SG, Bassett SH, Griffith WH, Mulcare DB, Swendseid ME: Further Observations on the Amino Acid Requirements of Older Men

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Thus, an integrated view on this molecule is required to more precisely understand its impact for metabolic diseases like type 2 diabetes