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Moreover, the obstruction of lymphatic drainage at the tumor site results in prolonged retention of nanoparticles within the tumor tissue

Raw data are available from the corresponding author upon reasonable request, subject to compliance with Chung Shan Medical University Hospital and TriNetX regulatory requirements and data sharing policies

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Further, the nuclear factor erythroid 2-related factor 2 (NRF2) pathway is a master regulator of antioxidant and cytoprotective gene expression, crucial for cellular defense against oxidative stress