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The role of glutamine in cancer cell growth Rapidly proliferating cancer cells take up glutamine from plasma via various amino acid transporters, and then it is converted to glutamate in the mitochondria by the two forms of glutaminase: kidney-type glutaminase (GLS)1 and liver-type GLS2 8

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If the population treated has similar clinical characteristics, but the settings are different (eg, frequency of follow-up visits, frequency physician/nurse contacts with patients, and adherence) are the results of RCTs transferrable to the real-world setting

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