2013;85(2):74552 Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D
Four -ketoacid dehydrogenase complexes ( Figure 4 ), including: (i) the pyruvate dehydrogenase complex that catalyzes the conversion of pyruvate to acetyl-coenzyme A (CoA), an important substrate for energy production via the citric acid cycle
3.3.2 Clinical evidence Clinical studies support a cardioprotective role for metformin in diabetic cardiomyopathy and related cardiac complications
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