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Data collected from a randomized, placebo-controlled, double-blind trial of liraglutide 3.0 mg, in which nausea was the most frequent adverse event, showed that greater weight loss was associated with transient nausea and vomiting in participants with obesity but without diabetes [50]

2) Taking the medication incorrectly (not on an empty stomach or not waiting the full 30 minutes before eating) can reduce effectiveness

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An understudied population Drugs like Ozempic, Wegovy and Zepbound are "glucagon-like peptide-1 receptor agonists," or GLP-1s, for short

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