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"Smaller players will likely need to demonstrate either superior tolerability, novel indication-specific efficacy, meaningfully different dosing convenience, or combination strategies that address limitations of current agents, particularly muscle loss, rather than simply competing on weight-loss magnitude alone," says Nadolsky

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These claims are typically filed by individuals who experience adverse effects, such as gastroparesis or abdominal pain, after taking the medication

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8, are based on recent evidence and expert opinion