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A meta-analysis of intervention studies (folic acid supplementation, fortified foods and natural folate sources) in individuals stratified by MTHFR C677T genotype included six randomized controlled trials and four quasi-experimental studies, each lasting 4 weeks and using doses of 400-1,670 g DFE

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Competitive pressures exist, particularly from other GLP-1 receptor agonists and emerging dual-acting agents, but Mounjaro's established clinical data and Lilly's strategic market access provide a strong competitive advantage

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2 Bridging the nutrition guidance gap for GLP-1 receptor agonist therapy assisted weight loss: lessons from bariatric surgery