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Once-Weekly Semaglutide in Adults With Overweight or Obesity (STEP-1 Trial, 2021) showed significant weight loss and metabolic improvements with weekly semaglutide + lifestyle intervention versus placebo

Conclusion Chest pain is not a typical side effect of semaglutide, but it is a symptom that demands respect and attention

Sattar N, McGuire DK, Pavo I, Weerakkody GJ, Nishiyama H, Wiese RJ, et al

Glucagon-like peptide 1(GLP-1) in biology and pathology

Treat Yourself: Invest in Staples That Make You Feel Great at Every Size Despite what a lot of really mean people want you to believe, being on a GLP-1 is not the easy way to lose weight